Cholinergic Genetic Effects on Health and Cognition in Older Adults: Longitudinal Analysis

Cindy Lustig
Professor, Department of Psychology, College of Literature, Science & the Arts


Using the HRS representative sample of approximately 20,000 Americans over the age of 50, this pilot examines how limits in cholinergic function are related to changes in measurements of attention, memory, and cognitive status and physiological health across multiple time points.


  • Jantz, T. & Lustig, C. 2018. Cholinergic genetic effects on health and cognition in older adults: Longitudinal analysis. 1st annual MiCDA Pilot Project Symposium. May 7, 2018, Ann Arbor, MI.
  • Jantz, T & Lustig, C. Depression interacts with cholinergic genetic variant to affect cognition in older adults. LIFE Spring Academy 2017. May 21-24, 2017 Ann Arbor, University of Michigan.
  • Jantz, T., Zhou, L., & Lustig. C. (2017). Genetic variance in cholinergic efficiency interacts with depression to impact cognition in later life. Poster presented at the Psychonomic Society Annual Meeting. Vancouver, British Columbia, Canada